Rock Band™ 3 recognizes my Squier® by Fender® Stratocaster® Guitar and Controller but does not respond as I strum the strings

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Why does Rock Band™ 3 recognize my Squier® by Fender® Stratocaster® Guitar and Controller but does not respond as I strum the strings?
In some limited instances your Squier by Fender Stratocaster Guitar and Controller may need to be reset by simply turning it off and then turning it back on using the power switch located on the back of the instrument. It is also suggested that you check to ensure you are using a fresh set of batteries.